Small Animal Products
Apometic® -

Forum Animal Health
Crown House, 2-8 Gloucester Road
Redhill, Surrey RH1 1FH
United Kingdom

Telephone: +44 (0)1737 781416
animalhealth@forumgroup.co.uk

Apometic® -

APOMETIC®10MG/ML SOLUTION
FOR INJECTION

PRESENTATION
Apometic solution for injection contains 10mg/ml apomorphine hydrochloride as a clear, colourless or almost colourless solution.

USES
Apometic is indicated to induce emesis in dogs that have, or are suspected to have, ingested substances that may be poisonous.

DOSAGE AND ADMINISTRATION
Dogs: 0.2 mg per kg bodyweight (0.02 ml/kg bodyweight), by subcutaneous injection. Weigh animals before treatment.

Use a 1ml syringe graduated to 0.01ml to facilitate accurate dosing

The dosing chart below is intended as a guide.


Apometic® -
Apometic® -

CONTRA-INDICATIONS, WARNINGS, ETC

Do not use in cases of depression of the central nervous system.

Do not use in cats and other species.
Do not use in cases of caustic poisoning or where gastric foreign bodies may be present.
Do not use in cases of poisoning due to pyrethroids.

Do not use in animals known to be hypersensitive to apomorphine or any other excipients.

Do not exceed the recommended dosage.
Emesis occurs rapidly (within 10 minutes).
If emesis is not induced following a single injection, repeated injections will also prove ineffective and should not be given.

Use of the product is not recommended if the poison was ingested, or suspected to be ingested, more than 2 hours previously.

The use of the product in cases of known or suspected hepatic impairment should be in accordance with a risk/benefit assessment by the responsible veterinarian.

Side-effects: Adverse effects include hypotension, drowsiness and/or sedation, dyskinesia and protracted vomiting.

The decrease in blood pressure is dosedependent. The maximum decrease in blood pressure is normally reached after 5 minutes following i.v. dose and the blood pressure returns to basal level after 10 to 30 minutes. No data are available on use during pregnancy, lactation or lay. Use only according to the benefit/risk assessment by the responsible veterinarian.

In the absence of compatibility studies, apomorphine must not be mixed with other veterinary medicinal products.

Operator warnings: Avoid accidental selfinjection. In case of accidental self-injection, seek medical advice immediately and show the package leaflet or label to the doctor. Avoid contact with skin and eyes. In case of contact with skin or eyes, rinse immediately with fresh water.

PHARMACEUTICAL PRECAUTIONS
Do not store above 25°C.

Store in the original package to protect from light.

The solution should be inspected visually prior to use. Only clear and colourless solutions should be used.

For single use only. Any unused solution should be discarded.

Dispose of any unused product and empty ampoules in accordance with guidance from your local waste regulation authority.

Keep out of reach of children.

For animal treatment only.

LEGAL CATEGORY
POM-V

PACKAGING QUANTITIES
Clear glass ampoules containing 2 ml solution for injection.

FURTHER INFORMATION
Dopamine antagonists (e.g. phenothiazines) may negate the emetic effect of apomorphine.

Overdose may result in respiratory and/ or cardiac depression, CNS stimulation or depression and protracted vomiting. Doses of 0.4 mg/kg - 1.6 mg/kg administered intravenously in dogs resulted in a short period of sedation followed by incessant running lasting from ½ to 1 hour from which the animals recovered. Naloxone may reverse the respiratory and CNS effects of the product but not the emetic effects.

This is a limited Marketing Authorisation. A full set of supporting efficacy data is not available for this product.

All suspected adverse reactions and any suspected lack of efficacy should be reported to 01737 781416 at Forum Animal Health, Crown House, 2-8 Gloucester Road, Redhill, Surrey RH1 1FH.

Further information on this product and its supporting data can be found on
http://www.vmd.defra.gov.uk/
ProductInformationDatabase/

MARKETING AUTHORISATION NUMBER
Vm 05928/4006.

GTIN (GLOBAL TRADE ITEM NUMBER)
Apometic 5x2ml Ampoule 05013073000391

For further information, please contact Forum Animal Health on
+44 (0)1737 781416 or
animalhealth@forumgroup.co.uk

Apometic® is a registered trade mark of Forum Products Ltd.

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